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Supplier
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Description
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Reference
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amadischem
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Rhein, 98%
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advtechind
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rheum palmatum root plant extract emodin,rhein
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advtechind
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rhein, certified reference material
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advtechind
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rhein tech 90%
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on request |
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250MG |
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on request |
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50MG |
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alfa-chemistry
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Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.IC50 value:Target:In vitro: Rhein (0.1 and 1 mg/mL) evidently suppressed cell proliferation and mitogen-activated protein (MAP) kinase activation in human colon adenocarcinoma cells (Caco-2) but significantly lessened H2O2-induced DNA damage and the elevated MDA and ROS levels induced by H2O2/Fe2+ at the concentrations of 0.1-10 mg/mL .In vivo: Oral administration of rhein (150 mg/kg/d) evidently ameliorated renal interstitial fibrotic lesions and attenuated the expression of α-SMA and deposition of fibronectin (FN) in mice with renal interstitial fibrosis induced by unilateral ureteral obstruction. Rhein also suppressed TGF-β1 and its type I receptor expression in obstructed kidneys . The biochemical parameters results of IgAN model rats showed that rhein-prevented and rhein-treated both improved the biochemical parameters and relieved renal pathological injury. The expressions of renal tissue TLR4, TGF-β1, but not TLR9 were significantly elevated in IgAN model rats (P < 0.05). Rhein-prevented and rhein-treated both inhibited TLR4 and TGF-β1 expressions ., 95%+
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leapchem
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rhein
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leapchem
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rhein
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alfa-chemistry
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Rhein, 95%+
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cm-finechemicals
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Rhein
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bocsci
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Rhein, > 98 %
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chemieliva
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4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid, 98%
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chemieliva
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Rhein, 98%
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rosewachem
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4,5-Dihydroxyanthraquinone-2-carboxylic Acid
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manchesterorganics
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1,8-Dihydroxyanthraquinone-3-carboxylic acid
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qcsrm
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Diacerein EP Impurity C
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biosynth
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bocsci
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Rhein, > 98 %
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advtechind
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rhein 95+%hplc
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activate-scientific
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4,5-Dihydroxyanthraquinone-2-carboxylic acid, 98%
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chempur
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1,8-Dihydroxy-3-carboxyanthraquinone/ 95%
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