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4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide |
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]phenyl]benzamide |
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Predict NMR spectrum
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InChI: |
1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) |
InChIKey: |
KTUFNOKKBVMGRW-UHFFFAOYSA-N |
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H donor: |
2 |
H acceptor: |
8 |
Rotatable bond: |
7 |
Stereocenter: |
0 |
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cLogP: |
4.346 |
cLogS: |
-4.383 |
Polar surface: |
86.28 |
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Supplier
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Description
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Reference
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amadischem
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Imatinib, 98%
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advtechind
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imatinib, 99%
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leapchem
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imatinib
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leapchem
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imatinib
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leapchem
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imatinib
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alfa-chemistry
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Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within tyrosine kinases (TK), thereby inhibiting ATP binding and preventing phosphorylation and the subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene as well as receptor TKs encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Imatinib was approved for medical use in the United States in 2001., >98%
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capotchem
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Imatinib, 98%(Min,HPLC)
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bocsci
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Imatinib, >98%
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chemieliva
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Imatinib (STI571), 98%
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lclabs
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Imatinib, Free Base
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biosynth
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qcsrm
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Imatinib
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rosewachem
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Imatinib
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bocsci
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Imatinib, >98%
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advtechind
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imatinib impurity 6
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25MG |
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on request |
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50MG |
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on request |
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chempur
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Imatinib/ >97%
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ivychem
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4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
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advtechind
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imatinib impurity 3
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001chemical
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Imatinib, NLT 98%
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advtechind
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imatinib, free base
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