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REF DUPL: Tacrolimus
Predict NMR spectrum
RN: 
104987-11-3
MF: 
C44H69NO12
MW: 
804.03136
InChI:  1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19-,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1
InChIKey:  QJJXYPPXXYFBGM-LJIGMGMYSA-N
H donor:  3
H acceptor:  13
Rotatable bond:  7
Stereocenter:  14
cLogP:  5.514
cLogS:  -5.676
Polar surface:  178.36
Permanent link: http://www.chemexper.com/search/cas/104987113.html Report error(s)
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  Supplier     Description     Reference  
bocsci Tacrolimus, >98%
on request
amadischem Tacrolimus, 98%
Bulk, semi-bulk
advtechind tacrolimus (fk-506), 99+%
on request
5G
advtechind tacrolimus, usp standard
on request
150MG
alfa-chemistry Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body’s learned (or adaptive) immune response.Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura’s disease, and the skin condition vitiligo.Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukuba, 98%+
1g
5g
10g
25g
100g
250g
leapchem tacrolimus, 98%
on request
leapchem tacrolimus
on request
leapchem tacrolimus
on request
capotchem Tacrolimus, 97%(Min,HLPC)
on request
cm-finechemicals FK506
Research
Pilot
chemieliva Tacrolimus (FK506), 98%
5G
10G
20G
50G
100G
50KG
lclabs FK-506
50 mg
100 mg
200 mg
500 mg
1 g
2 g
5 g
chemcube
Tacrolimus
 , >98%
on request
chemieliva Tacrolimus, 98%
5G
10G
20G
50G
100G
50KG
carbonesci Tacrolimus, 98%
on request
oakwood
Tacrolimus
10mg
biosynth
Tacrolimus monohydrate
on request
qcsrm Tacrolimus
bocsci Tacrolimus, >98%
on request
advtechind fk-506
500 MG
on request
5 G
on request
50 MG
on request
100 MG
on request
1 G
on request
2 G
on request
200 MG
on request

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